Funded by the Government of Ontario, BORN Ontario is a prescribed registry established under the Personal Health Information Protection Act, 2004. BORN Ontario is entrusted with a unique responsibility: to collect, curate, and mobilize vital data that empowers families, care providers, health systems, and policymakers – all in pursuit of healthier beginnings and brighter futures. BORN aspires to lead with excellence in the collection, analysis, and interpretation of perinatal and child health information, supporting high-quality care, informed decision-making, improved equity, and continuous system learning. As a learning health system, BORN also has a mission-driven research program to inform operations and help them achieve their strategic plan. Finally, BORN applies evidence-informed knowledge mobilization (KM) strategies to partner with end users, co-design innovations and knowledge products, disseminate findings, support adoption of BORN’s systems and products, and position their findings for implementation in the health system.